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J Korean Med Assoc > Volume 50(1); 2007 > Article
Lee and Park: Prevention and Treatment of Postoperative Nausea and Vomiting

Abstract

Postoperative nausea and vomiting is an adverse condition that affects a large number of patients after surgical interventions. Postoperative vomiting is a severe discomfort for patients and can be a bigger concern even than postoperative pain. Although many studies have been performed on the pathophysiology of postoperative nausea and vomiting, little has been known about it. This article reviews the risk factors, mechanisms, preventive measures, and treatment of postoperative nausea and vomiting.

References

1. Apfel CC, Roewer N, Krier C, Noldge-Schomburg G. Postoperative nausea and vomiting: improved understanding and better strategies Part I. Anasthesiol. Intensivmed. Notfallmed. Schmerzther 2004;39:490-501.

2. Kovac AL. Prevention and treatment of postoperative nausea and vomiting. Drugs 2000;59:213-243.

3. Gold BS, Kitz DS, Lecky JH, Neuhaus JM. Unanticipated admission to the hospital following ambulatory surgery. JAMA 1989;262:3003-3010.

4. Livingston EH, Passaro EP. Postoperative ileus. Dig Dis Sci 1990;35:121-132.

5. Kreis ME. Postoperative nausea and vomiting. Autonomic Neuroscience: Basic and Clinica 2006.

6. Belyansky LS, Sayenko VF, Furmanov JA, Churilova TJ. Bacterial translocation as a cause for septic complications in obstructive colonic ileus. Acta Chir Belg 2002;102:75-77.

7. Apfel CC, Korttila K, Abdalla M, Kerger H, Turan A, Vedder I, Zernak C, Danner K, Jokela R, Pocock SJ, Trenkler S, Kredel M, Biedler A, Sessler DI, Roewer N. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med 2004;350:2441-2451.

8. Palazzo MGA, Strunin L. Anaesthesia and emesis. I: etiology. Can Anaesth Soc J 1984;31:178-187.

9. Patel RI, Hanallah RS. Anesthetic complications following pediatric ambulatory surgery: a 3-year study. Anesthesiology 1988;69:1009-1012.

10. Larsson S, Jonmarker C. Postoperative emesis after pediatric strabismus surgery: the effect of dixyrazine compared to droperidol. Acta Anaesthesiol Scand 1990;34:227-230.

11. Hillsley K, Eeckhout C, Grundy D. Cilansetron acts at its site of absorption to antagonize the sensitivity of mesenteric afferent fibres to 5-hydroxytryptamine in the rat jejunum. Neurosci Lett 2000;278:137-140.

12. Henzi I, Walder B, Tramer MR. Dexamethasone for the prevention of postoperative nausea and vomiting: a quantitative systematic review. Anesth Analg 2000;90:186-194.

13. Tramèr MR. A rational approach to the control of postoperative nausea and vomiting. Evidence from systematic reviews. Part II. Recommendations for prevention and treatment, and research agenda. Acta Anaesthesiol Scand 2001;45:14-19.

14. Pierre S. Apfel's simplified score may favourably predict the risk of postoperative nausea and vomiting. Can J Anaesth 2002;49:237-242.

15. Apfel CC, Laara F, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology 1999;91:693-700.

16. Apfel CC, Kranke P, Katz MH, Goepfert C, Papenfuss T, Roewer N. Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design. Br J Anaesth 2002;88:234-240.

17. Henzi I, Walder B, Tramèr MR. Metoclopramide in the prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized, placebocontrolled studies. Anaesthesia 2002;57:1022-1027.

Figure 1
Hypothetical model of the pathophysiology of postoperative nausea and vomiting(5)
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Table 1
Risk of postoperative nausea and vomiting depending on the total score of risk factors(5)
jkma-50-65-i001-l.jpg
Table 2
Clinical management of postoperative nausea and vomiting (PONV) concerning prophylaxis and therapy(5)
jkma-50-65-i002-l.jpg


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