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J Korean Med Assoc > Volume 51(7); 2008 > Article
Kim: LINAC-based High-precision Radiotherapy: Radiosurgery, Image-guided Radiotherapy, and Respiratory-gated Radiotherapy

Abstract

High precision radiotherapy has been a hot issue to radiation oncologists for the last 100 years. Introduction of mega volt machine with linear accelerators changed the paradigm of radiotherapy, and development of computers and three-dimensional treatment opened the new era of high tech radiotherapy. However, the change and development in high tech radiotherapy for the last 10 years was much bigger than those of previous century, and it seems that we are very close to the finish line of high precision radiotherapy. Linear accelerator has been a firm base for such an evolution to high tech radiotherapy. It is the machine which is used most frequently for stereotactic radiosurgery, image-guided and respiratory gated radiotherapy and this review will introduce the basic concepts of this linac-based high precision radiotherapy.

References

1. Leksell L. The stereotaxic method and radiosurgery of the brain. Acta Chir Scand 1951;102:316-319.

2. Gros CM, Bur G, Veillon A. Radiosurgery of ovarian cancer. J Radiol Electrol Arch Electr Medicale 1954;35:132-133.

3. Timmerman RD, Kavanagh BD, Cho LC, Papiez L, Xing L. Stereotactic body radiation therapy in multiple organ sites. J Clin Oncol 2007;25:947-952.

4. Dawson LA, Eccles C, Craig T. Individualized image guided iso-NTCP based liver cancer SBRT. Acta Oncologica 2006;45:856-864.

5. Kavanagh BD, Schefter TE, Cardenes HR, Stieber VW, Raben D, Timmerman RD, McCarter MD, Burri S, Nedzi LA, Sawyer TE, Gaspar LE. Interim analysis of a prospective phase I/II trial of SBRT for liver metastases. Acta Oncologica 2006;45:848-855.

Figure 1
Linear accelerator of Varian (Palo Alto, CA, USA).
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Figure 2
Cyberknife, Accuray (Sunnyvale, CA, USA).
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Figure 3
Multi-leaf collimator.
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Figure 4
ExacTrac system, Brain Lab (Feldkirchen, Germany).
jkma-51-612-g004-l.jpg
Figure 5
On board imager (OBI) for Cone beam CT, Varian (Palo Alto, CA, USA).
jkma-51-612-g005-l.jpg
Figure 6
Respiratory gated radiotherapy.
jkma-51-612-g006-l.jpg
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