Gastrointestinal Motility Modulating Drugs

Oh Young Lee

doi:10.5124/jkma.2009.52.9.920

J Korean Med Assoc > Volume 52(9); 2009 > Article

Lee: Gastrointestinal Motility Modulating Drugs

Pharmacotherapeutics

Journal of the Korean Medical Association

Journal of the Korean Medical Association 2009; 52(9): 920-927.

Published online: September 30, 2009

DOI: http://dx.doi.org/10.5124/jkma.2009.52.9.920

Gastrointestinal Motility Modulating Drugs

Oh Young Lee, MD

Department of Internal Medicine, Hanyang University College of Medicine, Korea. leeoy@hanyang.ac.kr

Abstract

Gastrointestinal motility modulating drugs include all compounds which have pharmacological activity of modulating (stimulating or inhibiting) gastrointestinal motility. They are mainly used for the treatment of functional gastrointestinal diseases. Gastrointestinal motility modulating drugs include 5HT receptor agonists, antagonists, and antidopaminergic agents. Many new gastrointestinal motility modulating drugs are currently under investigation. The aims of this article are to review the mechanism of action, efficacy and side effects of the gastrointestinal motility modulating drugs.

Motility modulating drugs; Pharmacotherapy; Prokinetics; Functional gastrointestinal diseases

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