Uterine myomas are the most common benign pelvic tumors in reproductive aged women occurring in 25~40%. They may cause menstrual dysfunction, pressure symptoms and pain, subfertility, recurrent abortion and pregnancy-related problems. Treatment choices are variable and include observation, surgery, medication, myolysis, and uterine artery embolization. Most myomas are asymptomatic and can be followed serially with surveillance of growth and symptom development. For the choice of therapeutic modality the clinicians should understand many factors including age, parity, fertility preservation, extent and severity of symptoms, size and number of myomas, location, associated medical problems, possibility of malignancy, proximity to menopause and desire for uteine preservation. It is important to make an indivisualized treatment plan flexibly after considering and discussing risk/ benefit ratios and clinical situations.