Fluid therapy: classification and characteristics of intravenous fluids

Article information

J Korean Med Assoc. 2010;53(12):1103-1112
Publication date (electronic) : 2010 December 07
doi : https://doi.org/10.5124/jkma.2010.53.12.1103
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
Corresponding author: Ki-Young Lee, kylee504@yuhs.ac
Received 2010 October 18; Accepted 2010 November 03.

Abstract

Fluid and electrolyte therapies including nutritional support are markedly developing in medicine and many kinds of commercial fluids are being introduced to clinical practice. Understanding the characteristics and usefulness of intravenous fluids is necessary to manage patients properly. Disputes about the usefulness of crystalloid or colloid solutions for specific clinical conditions still continue. To make ideal fluid therapy possible, many kinds of fluids will be developed and applied to clinical practice in the near future by mimicking the composition and functions of human body fluids. The selection of crystalloid and colloid solutions for fluid therapy should be performed by considering patients' clinical and pathophysiological conditions and the characteristics and usefulness of each intravenous fluid.

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Article information Continued

Table 1

Calculations of fluid requirements by 4-2-1 rulea)

Table 1

a)Assumes a patient weighing 25 kg, resulting in an estimated fluid requirement of 65 mL/hr.

Table 2

Comparison of plasma and crystalloid infusion fluids

Table 2

a)lsolyte also contains phosphate (1 mEq/L).

Table 3

Comparative features of colloid

Table 3

Data from References 1, 12-14, and 17.

Table 4

Electrolyte concentration of balanced HES-preparations

Table 4

a)HES: hetastarch

Table 5

Crystalloids vs. colloids

Table 5