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J Korean Med Assoc > Volume 55(11); 2012 > Article
Park: Diagnosis and treatment of osteoporosis

Abstract

Osteoporosis is a common bone disease in postmenopausal women that leads to an increased risk of fracture. In osteoporosis, the bone mineral density (BMD) is reduced, and bone micro- and macroarchitecture deteriorates. Osteoporosis is defined by the World Health Organization as a BMD of 2.5 standard deviations or more below the mean peak bone mass (average of young and healthy adults) as measured by dual energy X-ray absorptiometry (DEXA). Diagnosis of osteoporosis can be made using BMD measurement. The most popular method of measuring BMD is DEXA. In treatment, we can use various exercises and nutritional supplementation, medications, and lifestyle modification for the prevention of fractures.

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Figure 1
PH change and gastric emptying time in the stomach after ingestion of alendronate and new one (From Hodges LA, et al. Int J Pharm 2012;432:57-62, according to the Creative Commons license) [24].
jkma-55-1083-g001-l.jpg
Table 1
Bone formation and resorption markers
jkma-55-1083-i001-l.jpg

S, serum; U, urine.



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