J Korean Med Assoc Search

CLOSE


J Korean Med Assoc > Volume 49(11); 2006 > Article
Pi and Kim: The Disease Spectrum in Premature Infants and the Progress of Pharmacological Treatment

Abstract

Liveborn infants delivered before 37 week of postmenstrual age or less than 2,500g of birth weight are defined as premature infants. Recently, the unprecedented progress in neonatal practice has achieved remarkable improvements in the survival of extremely premature infants. However, immature organ function and the complication of therapy still contribute to the high mortality and morbidity from a spectrum of disease especially in extremely premature, low birth weight infants; respiratory distress syndrome, chronic lung disease, necrotizing enterocolitis, intraventricular hemorrhage, nosocomial infection, and prolonged hospitalization consist of the spectrum of disease in premature infants. To achieve further progress in neonatal-perinatal practice, randomized clinical trials should be employed not just to test the effectiveness of new therapies but also to evaluate competing strategies toward evidence-based, better clinical practic

References

1. Muraskas J, Hasson A, Besinger RE. A girl with a birth weight of 280g, now 14 years old. New England Journal of Medicine 2004;351:836-837.

2. Fujiwara T, Konishi M, Chida S, Okuyama K, Ogawa Y, Nakamura H, et al. The Surfactant-TA Study Group. Surfactant replacement therapy with a single postventilatory dose of a reconstituted bovine surfactant in preterm neonates with respiratory distress syndrome: final analysis of a multicenter, double-blind, randomized trial and comparison with similar trials. Pediatrics 1990;86:753-764.

3. NIH Consensus Development Panel: Effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA 1995;273:413.

4. Tooley J, Dyke M. Randomized study of nasal continuous positive airway pressure in the preterm infant with respiratory distress syndrome. Acta Paediatrica 2003;92:1170-1174.

5. Dani C, Bertini G, Pezzati M, Cecchi A, Caviglioli C, Rubaltelli FF. Early extubation and nasal continuous positive airway pressure after surfactant treatment for respiratory distress syndrome among preterm infants <30 weeks' gestation. Pediatrics 2004;113:e560-e563.

6. Kinsella JP, Cutter GR, Walsh WF, Gerstmann DR, Bose CL, Abman SH, et al. Early inhaled nitric oxide therapy in premature newborns with respiratory failure. New England Journal of Medicine 2006;355:354-364.

7. Field D, Elbourne D, Truesdale A, Grieve R, Hardy P, Normand C, et al. INNOVO Trial Collaborating Group. Neonatal Ventilation With Inhaled Nitric Oxide Versus Ventilatory Support Without Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure: the INNOVO multicentre randomised controlled trial. Pediatrics 2005;115:926-923.

8. Yeh TF, Lin YJ, Lin HC, Huang CC, Hsieh WS, Tsai CH, et al. Outcomes at school age after postnatal dexamethasone therapy for lung disease of prematurity. New England Journal of Medicine 2004;350:1304-1313.

9. Schmidt B, Roberts RS, Davis P, Doyle LW, Barrington KJ, Tin W, et al. Caffeine for Apnea of Prematurity Trial Group. Caffeine therapy for apnea of prematurity. New England Journal of Medicine 2006;354:2112-2121.

10. Bandstra ES, Montalvo BM, Goldberg RN, Pacheco I, Ferrer PL, Bancalari E, et al. Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. Pediatrics 1988;82:533-542.

11. Fowlie PW, Davis PG. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database of Systematic Reviews 2002;3:CD000174.

12. Koch J, Hensley G, Roy L, Brown S, Ramaciotti C, Rosenfeld CR. Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less. Pediatrics 2006;117:1113-1121.

13. Cotton RB, Haywood JL, Fitzgerald GA. Symptomatic patent ductus arteriosus following prophylactic indomethacin. A clinical and biochemical appraisal. Biology of the Neonate 1991;60:273-278.

14. Gersony WM, Peckham GJ, Ellison RC, Miettinen OS, Nadas AS. Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study. Journal of Pediatrics 1983;102:895-906.

15. Seri I. Hydrocortisone and vasopressor-resistant shock in preterm neonates. Pediatrics 2006;117:516-518.

16. Section on Ophthalmology American Academy of Pediatrics. American Academy of Ophthalmology. American Association for Pediatric Ophthalmology and Strabismus. Screening examination of premature infants for retinopathy of prematurity. Pediatrics 2006;117:572-576.

TOOLS
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 0 Crossref
  •   Scopus
  • 899 View
  • 1 Download
Related articles in
J Korean Med Assoc


ABOUT
ARTICLE CATEGORY

Browse all articles >

ARCHIVES
FOR CONTRIBUTORS
Editorial Office
37 Ichon-ro 46-gil, Yongsan-gu, Seoul
Tel: +82-2-6350-6562    Fax: +82-2-792-5208    E-mail: jkmamaster@gmail.com                

Copyright © 2024 by Korean Medical Association.

Developed in M2PI

Close layer
prev next