Magnetic resonance imaging (MRI) requires the patients to remain completely immobile because it is very sensitive to motion artifacts. Therefore, for pediatric patients, deep sedation is required for successful MRI. Since pediatric patients are vulnerable to the complications of sedation, the most important goal is safety. For safe and successful sedation, assigning well trained anesthesiologists or non-anesthesiologist healthcare professionals for the procedure and suitable equipment, monitoring, and medications are necessary.