Myocardial SPECT

Dong Soo Lee

doi:10.5124/jkma.2003.46.3.180

J Korean Med Assoc > Volume 46(3); 2003 > Article

Lee: Myocardial SPECT

Special Issue

Recent Advances in Nuclear Medicine

Journal of the Korean Medical Association

Journal of the Korean Medical Association 2003; 46(3): 180-185.

Published online: March 31, 2003

DOI: http://dx.doi.org/10.5124/jkma.2003.46.3.180

Myocardial SPECT

Dong Soo Lee, M.D.

Department of Nuclear Medicine, Seoul National University College of Medicine & Hospital, Korea. dsl@plaza.snu.ac.kr

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This review described the diagnostic efficacy of gated myocardial SPECT and its cost-effectiveness. Normal findings on myocardial stress SPECT predict negligible hard cardiac events. This prognostic value of myocardial SPECT influences cost-effectiveness of the strategy of the diagnosis of coronary artery disease. Despite the cost of the SPECT itself, the strategy of angiography following myocardial SPECT was the most cost-effective. Gated SPECT yields information regarding myocardial contractility and help differentiate attenuation artefact. Using gated SPECT, perfusion and contraction coupling can be interpreted. The test-retest reproducibility of global and regional contractile function of gated myocardial SPECT was excellent. Gated myocardial SPECT could be used to Predict functional improvement of myocardial dysfunction and to acknowledge improvement of myocardial function. Performance of rest-24 hour delay Tl-201 SPECT for viability study was good. Rest Tl-201/ gated stress Tc-99m MIBI SPECT and 24-hour delay Tl-201 SPECT is a convenient method to diagnose coronary artery disease and myocardial viability.

Myocardial SPECT; Cost-effectiveness; Coronary artery disease; Viability

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