Nutritional support is one of the major advances in the history of medicine in the 20th century. Since Dudrick and associates (1968) achieved the first successful nutritional support in puppies and human infants with short bowel syndrome, this technology has expanded as a gospel throughout the world. We can supply almost all of the macro - and micro - nutrients and calories as much as we need. However, utilities of some specific nutrients have to be limited only by the defined metabolism and the pathophysiology under the concept of nutritional pharmacology. This paper is for a practical review of the nutritional support for physicians who are working in the primary and secondary care centers in this country.