Melasma
Article information
J Korean Med Assoc. 2002;45(10):1234-1241
Publication date (electronic) : 2016 August 09
doi :
https://doi.org/10.5124/jkma.2002.45.10.1234
Abstract
Melasma is a common acquired symmetric hypermelanosis characterized by irregular light to dark brown macules and patches on sunexposed areas of the skin. Its histopathologic characteristics are important for treatment. Melasma is characterized by epidermal hyperpigmentation possibly by both the increased number of melanocytes and the increased function of melanogenic enzymes over the dermal solar changes.
Until now, curative measures are not available for melasma. Current therapies include topical agents (retinoic acid, hydroquinone, steroids), peeling (Combes solution, glycolic acid, TCA), and lasers(Co2, Erbium-Yag, Q-switched).
Keywords: Melasma; Histopathology; Depigmenting agents
Article information Continued
Copyright © 2002 Korean Medical Association