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J Korean Med Assoc > Volume 45(2); 2002 > Article
Journal of the Korean Medical Association 2002;45(2):206-215.
Published online August 10, 2016.
DOI: https://doi.org/10.5124/jkma.2002.45.2.206   
Growth Hormone Therapy
Sung Woon Kim
The safe clinical practice of growth hormone(GH) replacement requires judgement of the overall GH status, however, there is no biological marker for this in adults. In addition, diverse actions of GH in healthy individuals render the assessment of optimal GH replacement difficult. As in other fields of clinical practice, strategies and protocols vary between centers, however, most physicians experienced in pituitary diseases agree that GH replacement should begin at low doses, and increased to the final maintenance dose. The adequacy replacement is best determined by combination of clinical response and serum IGF-I, level avoiding supraphysiological levels of this GH-dependent peptide. Actually, GH can reduce body fat and restore muscles, bones, and quality of life. Appropriate using of GH will elicit antiaging effects.
Key Words: Growth hormone, Replacement therapy, Abdominal obesity syndrome, Osteoporosis, Quality of life


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