Tingling Sensation on Hands and Feet is one of common sensory symptoms, which is frequently associated with not only peripheral nerve disorders, including polyneuropathies, entrapment neuropathies(carpal tunnel syndrome or tarsal tunnel syndrome) and radiculopathies, but also stroke or peripheral vascular diseases. Despite numerous conditions causing acroparesthesia, characteristic symptoms and signs of each category can afford to inform the critical differentiating clues like followings glove-stocking paresthesia in polyneuroapthy, dermatomal radiating paresthesia in radiculopathy, sensory level in myelopathy, and crossed paresthesia in brainstem lesion. In this review, diagnostic and therapeutic approach to acroparesthesia is schematically described. In addition, neuropathic pain, a special type of pain or unpleasant feeling caused by partial/complete denervation of sensory nervous systems, as one of common causes of acroparesthesia, will be discussed.